Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model

@inproceedings{Brunetti2014PantethineTI,
  title={Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model},
  author={Dario Brunetti and Sabrina Dusi and Carla Giordano and Costanza Lamperti and Michela Morbin and Valeria Fugnanesi and Silvia Marchet and Gigliola Fagiolari and O. C. M. Sibon and M. Moggio and Giulia d’Amati and Valeria Tiranti},
  booktitle={Brain : a journal of neurology},
  year={2014}
}
Pantothenate kinase-associated neurodegeneration, caused by mutations in the PANK2 gene, is an autosomal recessive disorder characterized by dystonia, dysarthria, rigidity, pigmentary retinal degeneration and brain iron accumulation. PANK2 encodes the mitochondrial enzyme pantothenate kinase type 2, responsible for the phosphorylation of pantothenate or… CONTINUE READING