Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins.

@article{Penuela2007Pannexin1A,
  title={Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins.},
  author={Silvia Penuela and Ruchi Bhalla and Xiang-qun Gong and Kyle N Cowan and Steven J Celetti and Bryce J. Cowan and Donglin Bai and Qing Shao and Dale W Laird},
  journal={Journal of cell science},
  year={2007},
  volume={120 Pt 21},
  pages={3772-83}
}
Pannexins are mammalian orthologs of the invertebrate gap junction proteins innexins and thus have been proposed to play a role in gap junctional intercellular communication. Localization of exogenously expressed pannexin 1 (Panx1) and pannexin 3 (Panx3), together with pharmacological studies, revealed a cell surface distribution profile and life cycle dynamics that were distinct from connexin 43 (Cx43, encoded by Gja1). Furthermore, N-glycosidase treatment showed that both Panx1 (approximately… CONTINUE READING
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