Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma.

@article{Peeters2012PanitumumabIC,
  title={Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma.},
  author={Marc Peeters and Allen Lee Cohn and C L Koehne and Jean-yves Douillard},
  journal={Clinical colorectal cancer},
  year={2012},
  volume={11 1},
  pages={14-23}
}
The fully human anti-epidermal growth factor receptor (EGFR) monoclonal antibody panitumumab has been shown to improve progression-free survival when administered as a monotherapy for patients with chemotherapy-refractory metastatic colorectal cancer (mCRC) and is approved in this setting. Two large randomized clinical trials have investigated panitumumab in combination with 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX) as a first-line therapy for mCRC and 5-fluorouracil, leucovorin, and… CONTINUE READING
7 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

Similar Papers

Loading similar papers…