Paneth cell α-defensins and enteric microbiota in health and disease

@inproceedings{Nakamura2016PanethC,
  title={Paneth cell α-defensins and enteric microbiota in health and disease},
  author={Kiminori Nakamura and Naoya Sakuragi and Akiko TAKAKUWA and Tokiyoshi Ayabe},
  booktitle={Bioscience of microbiota, food and health},
  year={2016}
}
Antimicrobial peptides are major effectors of innate immunity of multicellular organisms including humans and play a critical role in host defense, and their importance is widely recognized. The epithelium of the intestine is the largest surface area exposed to the outer environment, including pathogens, toxins and foods. The Paneth cell lineage of intestinal epithelial cells produces and secretes α-defensin antimicrobial peptides and functions in innate enteric immunity by removing pathogens… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 119 references

Decreased secretion of Paneth cell α-defensins in graft-versus-host disease.

Transplant infectious disease : an official journal of the Transplantation Society • 2015
View 1 Excerpt

Establishment of Intestinal Bacteriology

Bioscience of microbiota, food and health • 2014
View 1 Excerpt

Similar Papers

Loading similar papers…