Panel sequencing for clinically oriented variant screening and copy number detection in 142 untreated multiple myeloma patients

Abstract

We employed a customized Multiple Myeloma (MM)-specific Mutation Panel (M(3)P) to screen a homogenous cohort of 142 untreated MM patients for relevant mutations in a selection of disease-specific genes. M(3)Pv2.0 includes 77 genes selected for being either actionable targets, potentially related to drug-response or part of known key pathways in MM biology… (More)
DOI: 10.1038/bcj.2016.1

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