Pandoraviruses: Amoeba Viruses with Genomes Up to 2.5 Mb Reaching That of Parasitic Eukaryotes

@article{Philippe2013PandoravirusesAV,
  title={Pandoraviruses: Amoeba Viruses with Genomes Up to 2.5 Mb Reaching That of Parasitic Eukaryotes},
  author={N. Philippe and Matthieu Legendre and Gabriel Doutre and Y. Cout{\'e} and O. Poirot and M. Lescot and Defne Arslan and V. Seltzer and L. Bertaux and C. Bruley and J. Garin and J. Claverie and C. Abergel},
  journal={Science},
  year={2013},
  volume={341},
  pages={281 - 286}
}
  • N. Philippe, Matthieu Legendre, +10 authors C. Abergel
  • Published 2013
  • Biology, Medicine
  • Science
  • Zeus' Revenge Sediment-dwelling amoebae appear to have an unhappy affinity for huge viruses. Giant icosahedral Mimiviruses with genomes of the order of 1 megabase (Mb) were first identified in Acanthamoeba. Digging into antipodean sediments has once again been fruitful where Philippe et al. (p. 281; see the cover) discovered some enormous viruses in Acanthamoeba, visible by light microscopy and having genomes up to 2.5 Mb. The Pandoraviruses are phagocytosed by target cells and, after fusing… CONTINUE READING

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