Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis.

@article{Gupta1995PancytopeniaDT,
  title={Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis.},
  author={Pawan Gupta and Robert W. Hurley and P H Helseth and Jessica L. Goodman and Dale E. Hammerschmidt},
  journal={American journal of hematology},
  year={1995},
  volume={50 1},
  pages={60-2}
}
We present a case of hemophagocytosis during infection with the intraërythrocytic protozoan Babesia microti in a 47-year-old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop… CONTINUE READING
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