Pancuronium Reduces Halothane Requirement in Man

@article{Forbes1979PancuroniumRH,
  title={Pancuronium Reduces Halothane Requirement in Man},
  author={A. R. Forbes and N. Cohen and E. Eger},
  journal={Anesthesia & Analgesia},
  year={1979},
  volume={58},
  pages={497–499}
}
We studied the contribution of pancuronium to anesthetic requirement in man by comparing MAC for halothane alone in 18 patients, with that after intravenous administration of pancuronium, 0.1 mg/kg, in 17 patients. In each group, movement was observed in limbs isolated from the circulation by tourniquet. In patients receiving pancuronium, halothane MAC was 0.55%, whereas the control value was 0.73%. Thus pancuronium reduces halothane MAC by 25%. 
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