Pancuronium Reduces Halothane Requirement in Man

@article{Forbes1979PancuroniumRH,
  title={Pancuronium Reduces Halothane Requirement in Man},
  author={A. R. Forbes and N. Cohen and E. Eger},
  journal={Anesthesia & Analgesia},
  year={1979},
  volume={58},
  pages={497–499}
}
We studied the contribution of pancuronium to anesthetic requirement in man by comparing MAC for halothane alone in 18 patients, with that after intravenous administration of pancuronium, 0.1 mg/kg, in 17 patients. In each group, movement was observed in limbs isolated from the circulation by tourniquet. In patients receiving pancuronium, halothane MAC was 0.55%, whereas the control value was 0.73%. Thus pancuronium reduces halothane MAC by 25%. 
View on Wolters Kluwer
ncbi.nlm.nih.gov
62 Citations
Highly Influential Citations
1
Background Citations
19
Methods Citations
1
Results Citations
1

62 Citations

Citation Type

Citation Type

Reduction in Halothane MAC: Comparison of Morphine and Alfentanil
  • 35
The Influence of High Spinal Anesthesia on Sensitivity to Midazolam Sedation
  • 87
Effects of atracurium, vecuronium or pancuronium pretreatment on lignocaine seizure thresholds in cats.
  • 7
Response of lower esophageal contractility to changing concentrations of halothane or isoflurane: A multicenter study
  • 6
Midazolam‐Alfentanil Synergism for Anesthetic Induction in Patients
  • 80
How may neuromuscular blocking drugs affect the state of general anesthesia?
  • 3
Paralysis for ventilated patients? Yes or no?
  • 10
Esmolol Potentiates Reduction of Minimum Alveolar Isoflurane Concentration by Alfentanil
  • 80
Sugammadex at both high and low doses does not affect the depth of anesthesia or hemodynamics: a randomized double blind trial
  • 7
Assessment of immediate post-anaesthetic recovery in young children following intravenous morphine infusions, halothane, and isoflurane.
  • 4
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 17 REFERENCES
Effect of Nitrous Oxide and of Narcotic Premedication on the Alveolar Concentration of Halothane Required for Anesthesia
  • 234
The Relationship between Age and Halothane Requirement in Man
  • 275
The comparative potency and pharmacokinetics of pancuronium and its metabolites in anesthetized man.
  • 52
ELECTROENCEPHALOGRAPHIC STUDIES OF THE CURARIZED PATIENT
  • 18
The Effect of Curare and Curare-like Substances on the Central Nervous System
  • 26
Effects of d-tubocurarine on the frog sympathetic ganglion cell and on synaptic function.
  • 4
A neural basis of the anesthetic state.
  • 342
Elevation of lidocaine seizure threshold by gallamine in rhesus monkeys.
  • 4
The effects of depolarizing muscle relaxants on the electroencephalogram and the circulation during halothane anaesthesia in man.
  • 4
  • PDF
On biological assays requiring quanta1 responses
  • J Pharmacol Exp Ther
  • 1972
...
1
2
...