• Corpus ID: 33352941

Pancreaticoduodenal lymph flow and lipase activity in acute experimental pancreatitis.

  title={Pancreaticoduodenal lymph flow and lipase activity in acute experimental pancreatitis.},
  author={Mikl{\'o}s Papp and {\'E}va P. N{\'e}meth and Edit Horvath},
  volume={4 2},
Activity of the pancreatic digestive enzymes in thoracic duct lymph has been shown to increase in man after pancreatic stimulation by secretin (3, 5), impaired passage of the pancreatic juice into the duodenum (5), surgical trauma to the pancreas (5) and in the dog following ligation of the excretory ducts of the pancreas ( 4, 13, 16, l 7, l 9), enhancement of pancreatic secretion (1, 10, 19, 23) and injection of bile (6, 7, 18, 19) and trypsin (20, 21) into the pancreas. Thus, pancreatic… 

Tables from this paper

Absorption of pancreatic lipase from the duodenum into lymphatics
A significantly higher lipase activity was measured in the duodenal lymph samples of 15 dogs than in each of corresponding arterial blood plasma samples collected prior to, during and after maximal
Enzymfreisetzung und aktivierung der kallikrein-kinin-systeme bei experimenteller pankreatitis
In both pancreatitis groups there was evidence for activation of the tissue kallikreinkinin system in the form of an increase in the k allikrein concentration and a decrease in the kininogen concentration.
Impeded interstitial fluid movement: a factor in pancreatic oedema.
The results suggest that both the rise in lymph flow and pressure during the development of oedema in lobular organs like the pancreas are rather the consequences and not the causes of Oedema.
Alteration of membrane fusion as a cause of acute pancreatitis in the rat
The findings indicate severe changes in the specificity of the intracellular membrane fusion process induced by supramaximal doses of a pancreatic secretagogue, which finally result in autodigestion of the pancreas.
Lymphatic system of the pancreas
Rarely are there lymphatics associated with islets of Langerhans, and then only where lymphatic vessels in connective tissue septa pass close to a pancreatic lobule that contains an islet at its periphery.
Lymphatic Vessel Network Structure and Physiology.
A comprehensive review of important findings over the past century along with recent advances in the understanding of the anatomy and physiology of lymphatic vessels, including tissue/organ specificity, development, mechanisms of lymph formation and transport, lymphangiogenesis, and the roles of lymphatics in disease are provided.
Somatostatin in the Treatment of Acute Pancreatitis
The treatment of acute pancreatitis has markedly improved within the last 80 years. The lethality rate receded from 60% to a mean of 15–20%. However, this improvement was not due to any specific


Pathways of Enzymes into the Blood in Acute Damage of the Pancreas.∗
The concentrations of amylase and lipase in peripheral venous blood, portal blood, and thoracic duct lymph are equal in fasting anesthetized dogs, indicating that injury of the pancreas or retention of its secretion is due mainly to the inflow of pancreatic enzymes into the general circulation.
A fresh approach to the pathogenesis of pancreatitis.
A unifying concept of pathogenesis is presented which is compatible with known clinical and experimental facts and suggests new possibilities in the relationship between biliary tract disease and pancreatitis.
: lntra - acinar lipolysis , an early sign of intravHal pancreatic autodigcstion
  • Acta med . Acad . Sci . hung .
  • 1970
Experimcntellc Pankreatitis
  • Mikromcthode zur Bcstimmung der Pankreaslipasc im Scrum. Dtsch. med. Wschr
  • 1968
nesis of pancreatitis
  • Gut
  • 1968