Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion.

@article{Phillips2010PancreaticSC,
  title={Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion.},
  author={Phoebe A. Phillips and Lu Yang and Arthur Shulkes and Alain Vonlaufen and Anne Poljak and Sonia Bustamante and Alessandra Warren and Zhihong Xu and Michael Guilhaus and Romano Cesare Pirola and Minoti Vivek Apte and Jeremy Somers Wilson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 40},
  pages={17397-402}
}
The pancreatic secretagogue cholecystokinin (CCK) is widely thought to stimulate enzyme secretion by acinar cells indirectly via activation of the vagus nerve. We postulate an alternative pathway for CCK-induced pancreatic secretion. We hypothesize that neurally related pancreatic stellate cells (PSCs; located in close proximity to the basolateral aspect of acinar cells) play a regulatory role in pancreatic secretion by serving as an intermediate target for CCK and secreting the… CONTINUE READING