Pancreatic renin-angiotensin system: a novel target for the potential treatment of pancreatic diseases?


The hormonal renin-angiotensin system (RAS) has important physiological functions, which are related directly and indirectly to the regulation of blood pressure, fluid and electrolyte balance [1]. The potent vasoconstrictor action of angiotensin II (Ang II) originates from hepatic precursor angiotensinogen, where it is cleaved by the renal enzyme renin in… (More)