Pancreatic polypeptide and its central Y4 receptors are essential for cued fear extinction and permanent suppression of fear

@inproceedings{Verma2016PancreaticPA,
  title={Pancreatic polypeptide and its central Y4 receptors are essential for cued fear extinction and permanent suppression of fear},
  author={Dilip Verma and Birgit A. H{\"o}rmer and K Bellmann‐Sickert and V Thieme and A G Beck‐Sickinger and Herbert Herzog and G{\"u}nther Sperk and Ramon O Tasan},
  booktitle={British journal of pharmacology},
  year={2016}
}
BACKGROUND AND PURPOSE Avoiding danger and finding food are closely related behaviours that are essential for surviving in a natural environment. Growing evidence supports an important role of gut-brain peptides in modulating energy homeostasis and emotional-affective behaviour. For instance, postprandial release of pancreatic polypeptide (PP) reduced food intake and altered stress-induced motor activity and anxiety by activating central Y4 receptors. EXPERIMENTAL APPROACH We characterized [K… CONTINUE READING
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