Pancreatic lipase inhibitory activity of taraxacum officinale in vitro and in vivo

  title={Pancreatic lipase inhibitory activity of taraxacum officinale in vitro and in vivo},
  author={Jian Zhang and Min-Jung Kang and Myung-Jin Kim and Mi-Eun Kim and Ji-hyun Song and Young M. Lee and Jung-In Kim},
  booktitle={Nutrition research and practice},
Obesity has become a worldwide health problem. Orlistat, an inhibitor of pancreatic lipase, is currently approved as an anti-obesity drug. However, gastrointestinal side effects caused by Orlistat may limit its use. In this study the inhibitory activities of dandelion (Taraxacum officinale) against pancreatic lipase in vitro and in vivo were measured to determine its possible use as a natural anti-obesity agent. The inhibitory activities of the 95% ethanol extract of T. officinale and Orlistat… CONTINUE READING
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