Pancreatic islet function in omega3 fatty acid-depleted rats: Glucose metabolism and nutrient-stimulated insulin release.

@article{Oguzhan2006PancreaticIF,
  title={Pancreatic islet function in omega3 fatty acid-depleted rats: Glucose metabolism and nutrient-stimulated insulin release.},
  author={Berrin Oguzhan and Ying Zhang and Karim Louchami and Philippe Courtois and Laurence Portois and Jean-Michel Chardigny and Willy Jean Malaisse and Yvon A. Carpentier and Abdullah Sener},
  journal={Endocrine},
  year={2006},
  volume={29 3},
  pages={457-66}
}
In order to gain information on the determinism of the perturbation of fuel homeostasis in situations characterized by a depletion in long-chain polyunsaturated omega3 fatty acids (omega3), the metabolic and hormonal status of omega3-depleted rats (second generation) was examined. When required, these rats were injected intravenously 120 min before sacrifice with a novel medium-chain triglyceride-fish oil emulsion able to provoke a rapid and sustained increase of the omega3 content in cell… CONTINUE READING