Pancreatic endocrine insufficiency in posttransplant cystinosis.

@article{Fivush1987PancreaticEI,
  title={Pancreatic endocrine insufficiency in posttransplant cystinosis.},
  author={Barbara A. Fivush and Orville C. Green and Christopher C Porter and John Williamson Balfe and Sean O'regan and William A Gahl},
  journal={American journal of diseases of children},
  year={1987},
  volume={141 10},
  pages={
          1087-9
        }
}
Nephropathic cystinosis causes renal death by approximately age 10 years. With increased life span due to kidney transplantation, ten to 25 years of cystine accumulation has resulted in pancreatic complications in individuals with cystinosis. We noted severe hyperglycemia in five posttransplant patients, three of whom remained insulin-dependent diabetics several years after transplant. The clinical findings were not consistent with steroid-dependent or insulin-resistant diabetes. Pancreatic… CONTINUE READING
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