Pancreatic cancer: current understanding of molecular and genetic aetiologies.


Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancers where prognosis has not improved over the past few decades. However, there have been several advances in our understanding of the disease leading to earlier detection and targeted therapeutic treatment. It is now understood that specific somatic and germline mutations lead to the development… (More)
DOI: 10.1136/postgradmedj-2014-133161


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