Pancreatic cancer: Pancreatic tumour formation and recurrence after radiotherapy are blocked by targeting CD44

@article{Wood2014PancreaticCP,
  title={Pancreatic cancer: Pancreatic tumour formation and recurrence after radiotherapy are blocked by targeting CD44},
  author={Natalie J. Wood},
  journal={Nature Reviews Gastroenterology \&Hepatology},
  year={2014},
  volume={11},
  pages={73-73}
}
  • Natalie J. Wood
  • Published 21 January 2014
  • Medicine, Biology, Physics
  • Nature Reviews Gastroenterology &Hepatology
Pancreatic cancer: Pancreatic tumour formation and recurrence after radiotherapy are blocked by targeting CD44 

Expression of CD 44 in pancreatic cancer and its significance

Background: CD44 is a potentially interesting prognostic marker and therapeutic target in pancreatic cancer. The expression of CD44 has been reported to correlate with poor prognosis of pancreatic

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References

Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice.

TLDR
The TIC marker CD44s is up-regulated in human pancreatic tumors and associated with patient survival time, and strategies to target CD 44s cab be developed to block pancreatic tumor formation and post-radiotherapy recurrence in patients.