Pancreatic Epithelial Cells Form Islet-Like Clusters in the Absence of Directed Migration

@inproceedings{Holfinger2015PancreaticEC,
  title={Pancreatic Epithelial Cells Form Islet-Like Clusters in the Absence of Directed Migration},
  author={Steven Holfinger and James W Reinhardt and Rashmeet K. Reen and Kevin M Schultz and Kevin M. Passino and William Edward Ackerman and Douglas A. Kniss and Leonard M. Sander and Daniel Gallego-Perez and Keith J. Gooch},
  year={2015}
}
The endocrine differentiation of pancreatic ductal epithelial cells is dependent upon their transition from a twodimensional monolayer to three-dimensional islet-like clusters. Although clustering of these cells is commonly observed in vitro, it is not yet known whether clustering results from long-range signaling (e.g., chemotaxis) or short-range… CONTINUE READING