Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice.

@article{Lugea2006PancreasRF,
  title={Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice.},
  author={Aurelia Lugea and Li Nan and Samuel William French and Jorge A. Bezerra and Anna S. Gukovskaya and Stephen J Pandol},
  journal={Gastroenterology},
  year={2006},
  volume={131 3},
  pages={
          885-99
        }
}
BACKGROUND & AIMS The plasminogen (plg) system participates in tissue repair in several organs, but its role in pancreas repair remains poorly characterized. To understand better the role of plg in pancreas recovery following injury, we examined the course of cerulein-induced pancreatitis in plg-deficient and -sufficient mice. METHODS Pancreatitis was induced by cerulein administration (50 microg/kg, 7 intraperitoneal injections). Mice were killed either at the acute phase (7 hours after the… CONTINUE READING
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