Pamidronate treatment of chronic noninfectious inflammatory lesions of the mandible in children.

@article{CompeyrotLacassagne2007PamidronateTO,
  title={Pamidronate treatment of chronic noninfectious inflammatory lesions of the mandible in children.},
  author={Sandrine Compeyrot-Lacassagne and Alan M. Rosenberg and Paul Babyn and Ronald M. Laxer},
  journal={The Journal of rheumatology},
  year={2007},
  volume={34 7},
  pages={1585-9}
}
Noninfectious inflammatory lesions of the mandible occur in chronic recurrent multifocal osteomyelitis (CRMO). Diffuse sclerosing osteomyelitis of the mandible (DSOM) is a condition thought to be a localized form of CRMO. Recently, bisphosphonate therapy, and particularly intravenous pamidronate, has been proposed as a treatment for patients with both CRMO and DSOM who do not improve with nonsteroidal antiinflammatory drug treatment. We report our experience using pamidronate in 2 children with… CONTINUE READING