Palyosulfonoceramides A and B: Unique Sulfonylated Ceramides from the Brazilian Zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis

  title={Palyosulfonoceramides A and B: Unique Sulfonylated Ceramides from the Brazilian Zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis},
  author={Jos{\'e} Gustavo Lima Almeida and Ana Isabel V. Maia and Diego Veras Wilke and Edilberto Rocha Silveira and Raimundo Braz-Filho and James J. La Clair and Let{\'i}cia Veras Costa-Lotufo and Ot{\'i}lia Deusd{\^e}nia Loiola Pessoa},
  journal={Marine Drugs},
  pages={2846 - 2860}
The zoanthids Palythoa caribaeorum and Protopalythoa variabilis are among the most abundant marine species along the Brazilian coast. We now report the isolation and structure elucidation of two unprecedented sulfonylated ceramides, palyosulfonoceramide A (1) and palyosulfonoceramide B (2) from specimens collected off Brazil’s northeastern coast. The structures of 1 and 2 were established using a combination of NMR analyses, including: evaluation of 1H, 13C, 1H–1H COSY, 1H–13C HSQC, 1H–13C HMBC… 

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