Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain

@article{Hansen2010PalmitoylethanolamideAO,
  title={Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain},
  author={H. Hansen},
  journal={Experimental Neurology},
  year={2010},
  volume={224},
  pages={48-55}
}
  • H. Hansen
  • Published 2010
  • Biology, Medicine
  • Experimental Neurology
Acylethanolamides are formed in the brain "on demand" from membrane phospholipids called N-acylated phosphatidylethanolamines. The acylethanolamides are signaling molecules of lipid nature, and this lipofilicity suggests an autocrine function. The acylethanolamides include palmitoylethanolamide (PEA), oleoylethanolamide (OEA), stearoylethanolamide (SEA), and several other quantitative minor species including anandamide (= arachidonoylethanolamide). PEA and OEA can activate several different… Expand
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