Palmitoylethanolamide Reduces Early Renal Dysfunction and Injury Caused by Experimental Ischemia and Reperfusion in Mice

@article{Paola2012PalmitoylethanolamideRE,
  title={Palmitoylethanolamide Reduces Early Renal Dysfunction and Injury Caused by Experimental Ischemia and Reperfusion in Mice},
  author={R. di Paola and D. Impellizzeri and P. Mondello and E. Velardi and C. Aloisi and A. Cappellani and E. Esposito and S. Cuzzocrea},
  journal={Shock},
  year={2012},
  volume={38},
  pages={356–366}
}
ABSTRACT This study was designed to assess a protective effect of palmitoylethanolamide (PEA) in the development of inflammation after ischemia-reperfusion injury of the kidney. Moreover, to suggest a possible mechanism, renal ischemia-reperfusion was performed in mice with targeted disruption of peroxisome proliferator-activated receptor &agr; (PPAR-&agr;) gene (PPAR-&agr;KO) to explain whether the observed PEA effect was dependent on PPAR-&agr; pathway. Peroxisome proliferator-activated… Expand
35 Citations
Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury
  • 29
The anti-inflammatory effects of palmitoylethanolamide (PEA) on endotoxin-induced uveitis in rats.
  • 22
...
1
2
3
4
...

References

SHOWING 1-10 OF 51 REFERENCES
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury.
  • 132
Endogenous Interleukin-6 Enhances the Renal Injury, Dysfunction, and Inflammation Caused by Ischemia/Reperfusion
  • 161
  • PDF
High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury.
  • 73
  • PDF
Effects of Palmitoylethanolamide on Signaling Pathways Implicated in the Development of Spinal Cord Injury
  • 88
  • PDF
Inhibitors of poly (ADP‐ribose) synthetase reduce renal ischemia‐reperfusion injury in the anesthetized rat in vivo
  • 104
Glutamine treatment attenuates the development of ischaemia/reperfusion injury of the gut.
  • 52
Molecular Mechanisms of Acute Renal Failure following Ischemia/Reperfusion
  • 80
  • Highly Influential
...
1
2
3
4
5
...