Palmitoyl-L-carnitine acts like ouabain on voltage, current, and contraction in guinea pig ventricular cells.

Abstract

We previously showed that palmitoyl-L-carnitine (L-PC) inhibits the Na/K pump current (INa/K). In the present report, we test the hypothesis that L-PC, like ouabain, should increase myocyte shortening. Membrane potentials or ionic currents were recorded simultaneously with cell shortening in single guinea pig ventricular myocytes at room temperature (22… (More)

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