Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.

Abstract

Palmitate triggers inflammatory responses in several cell types, but its effects on cardiac fibroblasts are at present unknown. The aims of the study were to (1) assess the potential of palmitate to promote inflammatory signaling in cardiac fibroblasts through TLR4 and the NLRP3 inflammasome and (2) characterize the cellular phenotype of cardiac fibroblasts… (More)
DOI: 10.1016/j.bbalip.2016.11.003

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Cite this paper

@article{Sokolova2017PalmitatePI, title={Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.}, author={Marina Sokolova and Leif Erik Vinge and Katrine Alfsnes and Maria Belland Olsen and Lars Eide and Ole J\orgen Kaasb\oll and H{\aa}vard Attramadal and May-Kristin Torp and Linn E Fosshaug and Azita Rashidi and Egil Lien and Alexandra Vanessa Finsen and \Oystein Sandanger and P{\aa}l Aukrust and Trine Ranheim and Arne Yndestad}, journal={Biochimica et biophysica acta}, year={2017}, volume={1862 2}, pages={234-245} }