Palladium-catalyzed paraformaldehyde insertion: a three-component synthesis of benzofurans.

Abstract

An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction.

DOI: 10.1039/c6ob00198j

Cite this paper

@article{Cheng2016PalladiumcatalyzedPI, title={Palladium-catalyzed paraformaldehyde insertion: a three-component synthesis of benzofurans.}, author={Xiufang Cheng and Yi Peng and Jun Wu and Guo-Jun Deng}, journal={Organic & biomolecular chemistry}, year={2016}, volume={14 10}, pages={2819-23} }