Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: synthetic study of laurendecumallene B.

@article{Yoshimitsu2013PalladiumcatalyzedMF,
  title={Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: synthetic study of laurendecumallene B.},
  author={Yuji Yoshimitsu and Shinsuke Inuki and Shinya Oishi and Norihiko Fujii and Hiroaki Ohno},
  journal={Organic letters},
  year={2013},
  volume={15 12},
  pages={
          3046-9
        }
}
Palladium-catalyzed medium-ring formation from a cyclic propargyl carbonate via a ring-opening and -closing cascade proceeded at the central carbon atom of the propargyl unit to provide a tetrahydro-2H-oxocine derivative bearing the core structure of laurencia oxacycle. The synthetic application of this reaction to a possible laurendecumallene B precursor is also presented.