Palladium-Catalyzed Oxalyl Amide-Directed γ-Arylation of Aliphatic Amines.

@article{Han2015PalladiumCatalyzedOA,
  title={Palladium-Catalyzed Oxalyl Amide-Directed γ-Arylation of Aliphatic Amines.},
  author={Jian Han and Yongxiang Zheng and Chao Wang and Yan Zhu and Da-Qing Shi and Runsheng Zeng and Zhibin Huang and Yingsheng Zhao},
  journal={The Journal of organic chemistry},
  year={2015},
  volume={80 18},
  pages={9297-306}
}
A method for palladium-catalyzed oxalyl amide-directed arylation of α-unsubstituted aliphatic amines with aryl iodides has been developed. A wide variety of aryl iodides are tolerated in this transformation, affording various γ-arylpropylamine derivatives. Heterocyclic iodides can also be competent reagents in this γ-C(sp(3))-H bonds transformation.