Palifermin: Role in the Prevention of Chemotherapy- and Radiation-Induced Mucositis

  title={Palifermin: Role in the Prevention of Chemotherapy- and Radiation-Induced Mucositis},
  author={Anne M. McDonnell and Kristi L. Lenz},
  journal={Annals of Pharmacotherapy},
  pages={86 - 94}
Objective: To assess the efficacy, toxicity, and potential cost benefit of palifermin in the prevention of chemotherapy- and radiation-induced mucositis. Data Sources: MEDLINE and PubMed database searches were conducted (1966–May 2006) using the following search terms: palifermin, human keratinocyte growth factor, fibroblast growth factor, mucositis, and stomatitis. Study Selection And Data Extraction: All published clinical trials and abstracts examining the use of palifermin, as well as… 

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