Palette of fluorinated voltage-sensitive hemicyanine dyes.


Optical recording of membrane potential permits spatially resolved measurement of electrical activity in subcellular regions of single cells, which would be inaccessible to electrodes, and imaging of spatiotemporal patterns of action potential propagation in excitable tissues, such as the brain or heart. However, the available voltage-sensitive dyes (VSDs… (More)
DOI: 10.1073/pnas.1214850109


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@article{Yan2012PaletteOF, title={Palette of fluorinated voltage-sensitive hemicyanine dyes.}, author={Ping Yan and Corey D. Acker and Wen-liang Zhou and Peter Lee and Christian Bollensdorff and Adrian Negrean and Jacopo Lotti and Leonardo Sacconi and Srdjan D. Antic and Peter Kohl and Huibert D. Mansvelder and Francesco Pavone and Leslie M. Loew}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2012}, volume={109 50}, pages={20443-8} }