Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation.

  title={Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation.},
  author={Christian Lavialle and Guillaume Cornelis and Anne Dupresso{\'i}r and C{\'e}cile Esnault and Odile Heidmann and C{\'e}cile Vernochet and T. Heidmann},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  volume={368 1626},
The development of the emerging field of 'paleovirology' allows biologists to reconstruct the evolutionary history of fossil endogenous retroviral sequences integrated within the genome of living organisms and has led to the retrieval of conserved, ancient retroviral genes 'exapted' by ancestral hosts to fulfil essential physiological roles, syncytin genes being undoubtedly among the most remarkable examples of such a phenomenon. Indeed, syncytins are 'new' genes encoding proteins derived from… CONTINUE READING
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