Palaeogenomics: Genetic roots of the first Americans

  title={Palaeogenomics: Genetic roots of the first Americans},
  author={Jennifer A. Raff and Deborah A Bolnick},
The whole-genome sequence of a human associated with the earliest widespread culture in North America confirms the Asian ancestry of the Clovis people and their relatedness to present-day Native Americans. See Letter p.225 The Clovis complex is an archaeological culture distributed widely in North America. Dating to around 13,000 years ago it is characterized by distinct stone tools including a spear blade known as the Clovis point. Just who made these tools has been a subject of much… 

Clovis Colonization of Eastern North America: A Phylogenetic Approach

The basic method of cladistics is laid out and it is shown how it has formed the basis for long-term studies of the colonization of eastern North America during the Early Paleoindian period (ca. 13,300–11,900 calendar years before the present).

Does Mitochondrial Haplogroup X Indicate Ancient Trans-Atlantic Migration to the Americas? A Critical Re-Evaluation

Recently published genomic data from ancient and contemporary North Americans help clarify the population history of North America and the likely history of this haplogroup.

Demographic History of Indigenous Populations in Mesoamerica Based on mtDNA Sequence Data

Interestingly, although the European contact had a major negative demographic impact, a previous decline in Mesoamerica that had begun a few hundred years before is detected.

Late Pleistocene Human Skeleton and mtDNA Link Paleoamericans and Modern Native Americans

A near-complete human skeleton with an intact cranium and preserved DNA found with extinct fauna in a submerged cave on Mexico’s Yucatan Peninsula is described, which has Paleoamerican craniofacial characteristics and a Beringian-derived mitochondrial DNA (mtDNA) haplogroup (D1).

The repatriation of the Palaeoamericans: Kennewick Man/the Ancient One and the end of a non-Indian ancient North America

Abstract This article considers the repatriation of some the most ancient human skeletal remains from the United States as two sorts of ending: their end as objects of scientific study, and their end

Mitochondrial diversity of Iñupiat people from the Alaskan North Slope provides evidence for the origins of the Paleo- and Neo-Eskimo peoples.

The results yield insight into the maternal population history of the Alaskan North Slope and support the hypothesis that this region served as an ancestral pool for eastward movements to Canada and Greenland, for both the Paleo-Eskimo and Neo-ESkimo populations.

Native American Genomics and Population Histories

This review discusses the recent methodological advances and genetic studies that have improved the understanding of Native American genomics and population histories and synthesizes current knowledge about Native American genomic variation to build a model of population history in the Americas.

Dispersals of the Siberian Y-chromosome haplogroup Q in Eurasia

It is found that the subclades of haplogroup Q continued to disperse from Central Asia and Southern Siberia during the past 10,000 years.

Is Decrypting the Genetic Legacy of America’s Indigenous Populations Key to the Historicity of the Book of Mormon?

Page 1/22 10/27/2019 Abstract: The Book of

A Framework for the Initial Occupation of the Americas

  • D. Madsen
  • Environmental Science, Geography
  • 2015
Abstract A substantial amount of archaeological data suggests groups with markedly different lithic technologies and subsistence adaptations were widespread throughout both American continents by



Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans

The findings reveal that western Eurasian genetic signatures in modern-day Native Americans derive not only from post-Columbian admixture, as commonly thought, but also from a mixed ancestry of the First Americans.

Ancient human genome sequence of an extinct Palaeo-Eskimo

This genome sequence of an ancient human obtained from ∼4,000-year-old permafrost-preserved hair provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit.

Reconstructing Native American Population History

It is shown that the initial peopling followed a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America.

Beringian Standstill and Spread of Native American Founders

The newly resolved phylogenetic structure suggests that ancestors of Native Americans paused when they reached Beringia, during which time New World founder lineages differentiated from their Asian sister-clades, and a swift migration southward that distributed the founder types all the way to South America.

The genome of a Late Pleistocene human from a Clovis burial site in western Montana

The genome sequence of a male infant recovered from the Anzick burial site in western Montana is sequenced and it is shown that the gene flow from the Siberian Upper Palaeolithic Mal’ta population into Native American ancestors is also shared by the AnZick-1 individual and thus happened before 12,600 years bp.

Ancient DNA perspectives on American colonization and population history.

Although the broad genetic structure of American prehistoric populations appears to have been established relatively early, it is nevertheless identified examples of genetic discontinuity over time in select regions that may have implications for the interpretation of the genetic evidence for the initial colonization of the Americas and its subsequent population history.

Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European

An approximately 7,000-year-old Mesolithic skeleton discovered at the La Braña-Arintero site in León, Spain, is sequenceed to retrieve a complete pre-agricultural European human genome, providing evidence that a significant number of derived, putatively adaptive variants associated with pathogen resistance in modern Europeans were already present in this hunter-gatherer.

Genetic analysis of early holocene skeletal remains from Alaska and its implications for the settlement of the Americas.

This individual's mitochondrial DNA represents the founder haplotype of an additional subhaplogroup of haplogroup D that was brought to the Americas, demonstrating that widely held assumptions about the genetic composition of the earliest Americans are incorrect.

Reconciling migration models to the Americas with the variation of North American native mitogenomes

Most mtDNA variation (along the double-continent) stems from the first wave from Beringia, which followed the Pacific coastal route, which was accompanied or followed by a second inland migratory event, marked by haplogroups X2a and C4c, which affected all Amerindian groups of Northern North America.