Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments.

@article{Yamada2002PairwiseAD,
  title={Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments.},
  author={Soichiro Yamada and Denis Wirtz and Pierre A Coulombe},
  journal={Molecular biology of the cell},
  year={2002},
  volume={13 1},
  pages={382-91}
}
Most type I and II keratin genes are spatially and temporally regulated in a pairwise manner in epithelial tissues, where they represent the major structural proteins. Epithelia can be partitioned into simple (single-layered) and complex (multilayered) types. We compared the structural and mechanical properties of natural keratin polymers occurring in complex (K5-K14) and simple (K8-K18) epithelia. The intrinsic properties of these distantly related keratin filaments, whether dispersed or… CONTINUE READING

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