Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.

@article{Perry1985PairedHF,
  title={Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.},
  author={George Perry and Nicola Rizzuto and Lucila Autilio-Gambetti and Pierluigi Gambetti},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 11},
  pages={3916-20}
}
Neurofibrillary tangles from Alzheimer disease patients share antigenic determinants with neurofilaments and microtubule-associated proteins, as shown by light microscopy immunocytology. The present study addresses the issue of whether these determinants are located on the paired helical filaments or on other components of the neurofibrillary tangle. Sections from postmortem brains from Alzheimer disease patients were stained by using Bodian's silver method or immunostained by using poly- and… CONTINUE READING

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