Painful neuropathy with skin denervation after prolonged use of linezolid

@article{Chao2007PainfulNW,
  title={Painful neuropathy with skin denervation after prolonged use of linezolid},
  author={C. Chao and H.-Y. Sun and Y.-Ch. Chang and S. Hsieh},
  journal={Journal of Neurology, Neurosurgery, and Psychiatry},
  year={2007},
  volume={79},
  pages={97 - 99}
}
The prolonged use of linezolid, a new antibiotic against drug-resistant Gram-positive pathogens, might cause painful neuropathy. This finding raises the possibility that small-diameter sensory nerves in the skin, which are responsible for transmitting nociceptive information, might be affected. We report a 53-year-old female who developed pure small-fibre painful neuropathy (visual analogue scale, VAS = 82 on 0–100 scale) with marked skin denervation in the leg (epidermal nerve density, END = 2… Expand
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A 53-year-old female with pure small-fibre sensory neuropathy after prolonged use of linezolid is reported, and the relationship between skin innervation and corresponding neuropathic pain is documents. Expand
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