Painful diabetic neuropathy: treatment and future aspects.

  title={Painful diabetic neuropathy: treatment and future aspects.},
  author={Dan Ziegler},
  journal={Diabetes/metabolism research and reviews},
  volume={24 Suppl 1},
Around one of three diabetic patients is affected by distal symmetric polyneuropathy (DSP) which represents a major health problem, as it may present with partly excruciating neuropathic pain and is responsible for substantial morbidity and increased mortality. Treatment is based on four cornerstones: (1) multifactorial intervention aimed at (near)-normoglycaemia and reduction in cardiovascular risk factors, (2) treatment based on pathogenetic mechanisms, (3) symptomatic treatment, and (4… CONTINUE READING