Painful brachial plexopathies in SEPT9 mutations: adverse outcome related to comorbid states.

@article{Hoque2008PainfulBP,
  title={Painful brachial plexopathies in SEPT9 mutations: adverse outcome related to comorbid states.},
  author={Romy Hoque and Robert N Schwendimann and Roger Everett Kelley and Ricardo Bien-Willner and Kumaraswamy Sivakumar},
  journal={Journal of clinical neuromuscular disease},
  year={2008},
  volume={9 4},
  pages={379-84}
}
Hereditary neuralgic amyotrophy (HNA), an autosomal dominant disorder associated with SEPT9 mutation located on chromosome 17q25, causes recurrent painful weakness with sensory disturbances in a brachial distribution. We present electrophysiological, clinical phenotype, and molecular genetic data of three members from a family with HNA with the C262T SEPT9 mutation. The degree of motor weakness and recovery is variable within this family. Severity and recovery from motor deficits may have been… CONTINUE READING