Pain relief through expectation supersedes descending inhibitory deficits in fibromyalgia patients.

@article{Goffaux2009PainRT,
  title={Pain relief through expectation supersedes descending inhibitory deficits in fibromyalgia patients.},
  author={Philippe Goffaux and Juliana Barcellos de Souza and St{\'e}phane Potvin and Serge Marchand},
  journal={Pain},
  year={2009},
  volume={145 1-2},
  pages={18-23}
}
In healthy adults, expectations can modulate the activity of inhibitory bulbo-spinal projections, and can even block the analgesic properties of counter-irritation - a phenomenon that triggers descending inhibition. Since descending inhibition is known to be deficient in fibromyalgia (FM) patients, we tested the possibility that expectancy-mediated analgesia would improve, or even kick-start, the deficient inhibitory responses of FM patients. By measuring subjective pain ratings, spinal… CONTINUE READING