Pain in chronic pancreatitis: a salutogenic mechanism or a maladaptive brain response?

@article{Fregni2007PainIC,
  title={Pain in chronic pancreatitis: a salutogenic mechanism or a maladaptive brain response?},
  author={Felipe Fregni and Alvaro Pascual-Leone and Steven D. Freedman},
  journal={Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]},
  year={2007},
  volume={7 5-6},
  pages={411-22}
}
Pain in chronic pancreatitis is frequently refractory to medical and even surgical treatment. This refractoriness leads us to believe that a pancreas-independent, brain-mediated mechanism must be responsible. If so, several scenarios are worth considering. First, chronic pain could be the consequence of undesirable neuroplastic changes, by which pathology becomes established and causes disability. Alternatively, pain may be linked to the salutogenic (from salutogenesis, the Latin word for… CONTINUE READING
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