Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats

@article{Sieve2000PainAN,
  title={Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats},
  author={A. Sieve and T. King and Adam R Ferguson and J. Grau and M. Meagher},
  journal={Psychopharmacology},
  year={2000},
  volume={153},
  pages={180-190}
}
Abstract. Rationale: The anxiogenic DMCM, an inverse benzodiazepine agonist, was used to explore the relationship between negative affective states and pain. Past work suggests that the outcome obtained may depend on both the intensity of the affective state and the way in which pain is inferred. Objectives: The present study was designed to test the impact of relatively low doses of DMCM on multiple measures of pain reactivity and learning. Methods: In experiment 1, systemic injections of 0.00… Expand
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