PageRank-based identification of signaling crosstalk from transcriptomics data: the case of Arabidopsis thaliana.

@article{Omranian2012PageRankbasedIO,
  title={PageRank-based identification of signaling crosstalk from transcriptomics data: the case of Arabidopsis thaliana.},
  author={Nooshin Omranian and Bernd Mueller-Roeber and Zoran Nikoloski},
  journal={Molecular bioSystems},
  year={2012},
  volume={8 4},
  pages={1121-7}
}
The levels of cellular organization, from gene transcription to translation to protein-protein interaction and metabolism, operate via tightly regulated mutual interactions, facilitating organismal adaptability and various stress responses. Characterizing the mutual interactions between genes, transcription factors, and proteins involved in signaling, termed crosstalk, is therefore crucial for understanding and controlling cells' functionality. We aim at using high-throughput transcriptomics… CONTINUE READING

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