Pafuramidine for Pneumocystis jiroveci pneumonia in HIV-infected individuals

@article{Chen2007PafuramidineFP,
  title={Pafuramidine for Pneumocystis jiroveci pneumonia in HIV-infected individuals},
  author={Donald S Chen and R Marsh and Judith A. Aberg},
  journal={Expert Review of Anti-infective Therapy},
  year={2007},
  volume={5},
  pages={921 - 928}
}
Pneumocystis jiroveci pneumonia remains one of the major worldwide contributors to the morbidity and mortality of those with HIV infection. The mainstay of therapy for treatment is trimethoprim–sulfamethoxazole (TMP–SMX); however TMP–SMX may be associated with significant side effects and intolerability. In addition, TMP–SMX has a moderate pill burden with three- to four-times daily dosing schedule. Patients unable to tolerate TMP–SMX are confronted with either parenteral therapy or other oral… 
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