Paeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis

@inproceedings{Su2012PaeonolPM,
  title={Paeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis},
  author={Shan-Yu Su and Chin-Yi Cheng and Tung-Hu Tsai and Ching-Liang Hsieh},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2012}
}
Poststroke dementia commonly occurs following stroke, with its pathogenesis related to β-amyloid production and apoptosis. The present study evaluate the effects of paeonol, one of the phenolic phytochemicals isolated from the Chinese herb Paeonia suffruticosa Andrews (MC), on protection from memory loss after ischemic stroke in the subacute stage. Rats were subjected to transient middle cerebral artery occlusion (tMCAo) with 10 min of ischemia. The data revealed that paeonol recovered the step… CONTINUE READING
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