Paediatric gastroenteritis in the eastern Malaysian state of Sarawak: an epidemiological and clinical study.

Abstract

Over a period of 2 months, 35 of 69 (51%) cases of juvenile diarrhoea studied in eastern Malaysia were associated with rotavirus excretion; rotavirus associated diarrhoea occurred most commonly in the 6-24 month age group. Polyacrylamide gel electrophoresis (PAGE) of genome ribonucleic acid showed that only 4 rotavirus electropherotypes could be detected. Of those, 2 predominated and 2 were detected only once each; one of these may have been a reassortment of the two predominant electropherotypes. Analysis of the clinical features of patients excreting rotavirus subgroup 1 or 2, determined by PAGE, demonstrated that rotavirus subgroup 1 was associated with more hypotonic dehydration and need for intravenous therapy: lethargy was significantly more common among those excreting rotavirus subgroup 2.

Cite this paper

@article{Barker1988PaediatricGI, title={Paediatric gastroenteritis in the eastern Malaysian state of Sarawak: an epidemiological and clinical study.}, author={Ruth A Barker and Patrick Henry Maxwell and Cheol Pyo Hong and Matthew Cordery and Ian L Chrystie}, journal={Transactions of the Royal Society of Tropical Medicine and Hygiene}, year={1988}, volume={82 6}, pages={898-901} }