Paclitaxel suppresses the growth of primary prostate tumours (RM-1) and metastases in the lung in C57BL/6 mice.

@article{Zhang2006PaclitaxelST,
  title={Paclitaxel suppresses the growth of primary prostate tumours (RM-1) and metastases in the lung in C57BL/6 mice.},
  author={An Ling Zhang and P. J. Russell},
  journal={Cancer letters},
  year={2006},
  volume={233 1},
  pages={185-91}
}
Paclitaxel has potent anti-cancer effects through its ability to block metaphase/anaphase transition during cell mitosis. This study shows that paclitaxel can significantly suppress both primary orthotopic murine (RM-1) prostate tumour growth (up to 60%) and the formation of pseudometastatic tumour colony formation in the lungs (by up to 46%) in C57BL/6… CONTINUE READING