Paclitaxel release from single and double-layered poly(DL-lactide-co-glycolide)/poly(L-lactide) film for biodegradable coronary stent application.

@article{Lao2008PaclitaxelRF,
  title={Paclitaxel release from single and double-layered poly(DL-lactide-co-glycolide)/poly(L-lactide) film for biodegradable coronary stent application.},
  author={Luciana Lisa Lao and Subbu S Venkatraman},
  journal={Journal of biomedical materials research. Part A},
  year={2008},
  volume={87 1},
  pages={1-7}
}
Our laboratory has been developing a completely biodegradable coronary stent which is made of bilayers of biodegradable polyesters. This article presents the preliminary work done to exploit the drug delivery potential of such a polymeric stent. An antiproliferative drug (paclitaxel) was added either only to the top layer or to both layers and the in vitro… CONTINUE READING