Paclitaxel production by plant-cell-culture technology.

  • Homare Tabata
  • Published 2004 in Advances in biochemical engineering/biotechnology

Abstract

Plant cells catalyze multiple-step reactions of secondary metabolite biosynthesis, and selectively synthesize chiral compounds with polycyclic structures. Taking advantage of this characteristic, we studied the production of the anticancer drug paclitaxel, which is currently produced in limited supply. Callus culture investigations indicate that woody plant… (More)

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