Paclitaxel-based chemoradiotherapy in localized gastric carcinoma: degree of pathologic response and not clinical parameters dictated patient outcome.

@article{Ajani2005PaclitaxelbasedCI,
  title={Paclitaxel-based chemoradiotherapy in localized gastric carcinoma: degree of pathologic response and not clinical parameters dictated patient outcome.},
  author={Jaffer A. Ajani and Paul F. Mansfield and Christopher H. Crane and Tsung Teh Wu and Simon Lunagomez and Patrick M. Lynch and Nora Anita Janjan and Barry Feig and Josephine Faust and James C. Yao and Rebecca Nivers and Jackie Morris and Peter W. T. Pisters},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2005},
  volume={23 6},
  pages={1237-44}
}
PURPOSE Preoperative chemoradiotherapy may increase the R0 (curative) resection rate, overall survival (OS) duration, and disease-free survival (DFS) duration. We evaluated paclitaxel-based induction chemotherapy and chemoradiotherapy in patients with localized gastric or gastroesophageal adenocarcinoma to determine its feasibility, impact on the R0 resection rate, type of pathologic response, OS, and DFS. PATIENTS AND METHODS Patients with operable, localized gastric, or gastroesophageal… CONTINUE READING
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