Paclitaxel as a component of initial chemotherapy of advanced ovarian cancer: is the controversy resolved

@article{Markman1998PaclitaxelAA,
  title={Paclitaxel as a component of initial chemotherapy of advanced ovarian cancer: is the controversy resolved},
  author={Maurie Markman},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={1998},
  volume={124},
  pages={1-3}
}
Less than a decade ago, paclitaxel, a natural product of the Pacific Yew tree, was shown to produce objective antitumor responses in approximately 20 ± 40% of patients with platinum-refractory ovarian cancer (McGuire et al. 1989; Thigpen et al. 1994; Eisenhauer et al. 1994; Rowinsky and Donehower 1995). This observation led to the rapid incorporation of… CONTINUE READING