Pacific steelhead (Oncorhynchus mykiss) exposed to chlorpyrifos: benchmark concentration estimates for acetylcholinesterase inhibition.

@article{Sandahl2002PacificS,
  title={Pacific steelhead (Oncorhynchus mykiss) exposed to chlorpyrifos: benchmark concentration estimates for acetylcholinesterase inhibition.},
  author={Jason F. Sandahl and Jeffrey J. Jenkins},
  journal={Environmental toxicology and chemistry},
  year={2002},
  volume={21 11},
  pages={2452-8}
}
Steelhead trout (Oncorhynchus mykiss) were exposed for 96 h to the organophosphate chlorpyrifos to establish benchmark concentration (BMC) values in the low-effect range of brain acetylcholinesterase (AChE) inhibition. The U.S. Environmental Protection Agency (U.S. EPA) benchmark dose software was used to model the data. Benchmark concentrations were determined for a range of inhibition levels at 5, 10, and 20%, at 1 and 2 control standard deviations (SD), and at an experimental limit-of… CONTINUE READING